Searchable abstracts of presentations at key conferences in endocrinology

ea0081oc1.4 | Oral Communications 1: Diabetes, Obesity, Metabolism and Nutrition 1 | ECE2022

β-Caryophyllene, a dietary CB2 receptor selective cannabinoid mitigates myocardial fibrosis in a mice model of diabetic cardiomyopathy

Hashiesh Hebaallah Mamdouh , Sheikh Azimullah , Meeran MF Nagoor , Al Kaabi Ahmed , Sadek Bassem , Adeghate Ernest , Ojha Shreesh Kumar

β-Caryophyllene, a dietary CB2 receptor selective cannabinoid mitigates myocardial fibrosis in a mice model of diabetic cardiomyopathyBackground and aim: Diabetic cardiomyopathy (DCM), a cardiac complication in diabetes is characterized by abnormal cardiac function accompanied with myocardial fibrosis. In recent years, the cannabinoid type 2 receptors (CB2) emerged as a crucial therapeutic target for diabetes and its complications. The downregulatio...